All anabolic steroids have a tendency to reduce HDL (good) cholesterol and increase LDL (bad) cholesterol. The relative impact of an anabolic/androgenic steroid on serum lipids is dependant on the dose, route of administration (oral vs. injectable) type of steroid (aromatizable or non-aromatizable) and level of resistance to hepatic metabolism. With regards to nandrolone at a dose of 600mg per week over 10 weeks demonstrated 26% reduction in HDL cholesterol levels. This suppression is slightly greater than an equal dose of testosterone over an equal period. In other words it shows a slightly more negative impact on HDL/LDL ratio with nandrolone than with testosterone cypionate. It’s always recommended to accompany the use of this product with a low saturated fat diet and a cardiovascular exercise program.
In the largest (1996) reanalysis of previous studies of hormonal contraceptives and breast cancer risk, less than 1% were POP users. Current or recent POP users had a slightly increased relative risk (RR ) of breast cancer diagnosis that just missed being statistically significant. The relative risk was similar to that found for current or recent COCP users (RR ), and, as with COCPs, the increased relative risk decreased over time after stopping, vanished after 10 years, and was consistent with being due to earlier diagnosis or promoting the growth of a preexisting cancer.