Equipoise vs test

Results   Of 14 671 patients, 7332 were randomized to sitagliptin and 7339 to placebo. Hospitalization for HF occurred in % (n = 228) and % (n = 229) of the sitagliptin and placebo groups, respectively (unadjusted hazard ratio, ; 95% CI, -). There was also no difference in total hHF events between the sitagliptin (n = 345) and placebo (n = 347) groups (unadjusted hazard ratio, ; 95% CI, -). Post-hHF all-cause death was similar in the sitagliptin and placebo groups (% vs %, respectively), as was CV death (% vs %, respectively). No heterogeneity for the effect of sitagliptin on hHF was observed in subgroup analyses across 21 factors ( P  > .10 for all interactions). Meta-analysis of the hHF results from the 3 reported DPP4i CV outcomes trials revealed moderate heterogeneity ( I 2  = , P  = .16).


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Packages : 750ml bottles
Category : Stainless Steel Fermented
ABV : %   FG :   IBU : 25 
Water : Hill Country Well Water
Grains : Vienna Malt, Munich Malt, Pilsner Malt
Hops : Perle
Fermentation : Farmhouse Yeast, Native Yeast and Souring Bacteria from the Texas Hill Country
Last Release : Batch 3, bottled 7/6/2015 & 7/7/2015

Contains no animal products

Results   Among 371 randomized patients (mean [SD] age, [] years; 136 [%] women), 371 completed the trial. The proportion of patients with successful first-pass intubation did not differ significantly between the video laryngoscopy and direct laryngoscopy groups (% vs %; absolute difference, −% [95% CI, −% to %]; P  = .60). The proportion of first-attempt intubations performed by nonexperts (primarily residents, n = 290) did not differ between the groups (% with video laryngoscopy vs % with direct laryngoscopy; absolute difference % [95% CI, −% to %]; P  = .76). The median time to successful intubation was 3 minutes (range, 2 to 4 minutes) for both video laryngoscopy and direct laryngoscopy (absolute difference, 0 [95% CI, 0 to 0]; P  = .95). Video laryngoscopy was not associated with life-threatening complications (24/180 [%] vs 17/179 [%] for direct laryngoscopy; absolute difference, % [95% CI, −% to %]; P  = .25). In post hoc analysis, video laryngoscopy was associated with severe life-threatening complications (17/179 [%] vs 5/179 [%] for direct laryngoscopy; absolute difference, % [95% CI, % to %]; P  = .01) but not with mild to moderate life-threatening complications (10/181 [%] vs 14/181 [%]; absolute difference, −% [95% CI, −% to %]; P  = .37).

1) You give 1 anecdotal example, and in turn suggest that somehow that means the British have always been conservative? I remind you that it is almost a FULL CENTURY since the incident you mentioned and both medicine and medical sciences have made signficiant strides across all countries. Please provide some more recent examples
2) The whole point here is that this “medicine” offered in the US is not even in experimental stages… It has been tested in a different group of people but to date has not been experimented in the population with Charlie Gard’s mutation — hence there’s no evidence that it would actually work, unlike the insulin case you brought up.

Equipoise vs test

equipoise vs test

1) You give 1 anecdotal example, and in turn suggest that somehow that means the British have always been conservative? I remind you that it is almost a FULL CENTURY since the incident you mentioned and both medicine and medical sciences have made signficiant strides across all countries. Please provide some more recent examples
2) The whole point here is that this “medicine” offered in the US is not even in experimental stages… It has been tested in a different group of people but to date has not been experimented in the population with Charlie Gard’s mutation — hence there’s no evidence that it would actually work, unlike the insulin case you brought up.

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